The principal therapeutic motion of oxycodone is analgesia. Like all complete opioid agonists, there isn't a ceiling effect for analgesia with oxycodone.

Abruptly halting this medication may well result in withdrawal, particularly when you may have used it for a very long time or in significant doses. To avoid withdrawal, your medical doctor may perhaps decrease your dose slowly.

When discontinuing PERCOCET, slowly taper the dosage employing a individual-unique strategy that considers the following: the dose of PERCOCET the individual continues to be taking, the duration of procedure, and the Actual physical and psychological attributes in the affected person. To Increase the likelihood of A prosperous taper and reduce withdrawal signs, it is necessary the opioid tapering routine is agreed upon with the affected person.

Absorption of acetaminophen is speedy and Practically complete in the GI tract soon after oral administration. With overdosage, absorption is comprehensive in four several hours.

Acute or severe bronchial bronchial asthma in an unmonitored setting or while in the absence of resuscitative devices [see WARNINGS]

Anticholinergic Prescription drugs The concomitant utilization of anticholinergic medication may well boost chance of urinary retention and/or serious constipation, which can bring about paralytic ileus.

Oxycodone Hydrochloride and Acetaminophen is offered in tablets for oral administration. Each and every tablet for oral administration, is made up of oxycodone hydrochloride and acetaminophen in the following strengths:

The specific mechanism from the analgesic motion is mysterious. Nevertheless, specific CNS opioid receptors for endogenous compounds with opioid-like action are actually recognized throughout the Mind and spinal wire and they are imagined to play a task within the analgesic effects of this drug.

Have not furnished enough analgesia, or aren't envisioned to offer ample analgesia CONTRAINDICATIONS

Misuse and abuse of PERCOCET increases chance of overdose, which may cause central anxious system and respiratory melancholy, hypotension, seizures, and Dying. The danger is greater with concurrent abuse of PERCOCET with Liquor and also other CNS depressants.

Even though it can help Many of us, this medication may possibly often cause addiction. This danger could be greater if you have a material use dysfunction (for example overuse of or dependancy to medication/Liquor).

Advise patients that anaphylaxis continues to be reported with elements contained in oxycodone and acetaminophen tablets. Recommend patients how to recognize such a reaction and when to seek medical consideration [see CONTRAINDICATIONS, ADVERSE REACTIONS].

Suggest sufferers not to perform this sort of tasks right until they know how they may respond to your medication [see Safety measures].

In individuals who may be prone to the intracranial outcomes website of CO2 retention (e.g., Individuals with proof of enhanced intracranial tension or Mind tumors), oxycodone and acetaminophen tablets could decrease respiratory generate, and the resultant CO2 retention can additional improve intracranial stress.